Protein Blast

In your opinion, what are the pluses and minuses for Delta-BLAST compared to PSI-BLAST?

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Bioinformatic Homework. 1.How and/or why HMM could be useful in Biotechnology? 2.In your opinion, what are the pluses and minuses for Delta-BLAST compared to PSI-BLAST? 3.Discuss pros and cons of PSI-BLAST in compared to the regular protein BLAST (blastp)? 4.How would you assess homology in putative homologs found by PSI-BLAST