Based on the colors and the distribution, from which of the three domains of life are the majority of hits?The proteasome sequence is from a hyperthermophilic archaeon. Why do you suppose there may be a (relative) lack of total hits in archaea using HMMER?
Bioinformatics 1. 1. Run a Delta-BLAST with the silkworm insulin protein (P26726). Limit to human proteins in the RefSeq_Protein database. a. How many total sequences? b. How many human homologs appear to have the insulin domain (irrespective of the e-value threshold)? c. Now edit search remove the human from the organism selection and change DELTA-BLAST … Read more