Among adults and adolescents with Major Depressive Disorder (MDD), Dysthymia, and Subsyndromal Depression, who are started on an SSRI and who are compliant with treatment but fail to improve either fully, partially, or have no response, what is the benefit (efficacy oreffectiveness) of monotherapy and combined therapy?

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Prescribing Medications

Among adults and adolescents with Major Depressive Disorder (MDD), Dysthymia, and Subsyndromal Depression, who are started on an SSRI and who are compliant with treatment but fail to improve either fully, partially, or have no response, what is the benefit (efficacy oreffectiveness) of monotherapy and combined therapy?

Source: www.effectivehealthcare.ahrq.gov