In your opinion, what are the pluses and minuses for Delta-BLAST compared to PSI-BLAST?

Bioinformatic Homework.

1.How and/or why HMM could be useful in Biotechnology?

2.In your opinion, what are the pluses and minuses for Delta-BLAST compared to PSI-BLAST?

3.Discuss pros and cons of PSI-BLAST in compared to the regular protein BLAST (blastp)?

4.How would you assess homology in putative homologs found by PSI-BLAST